Fresno Man Killed on Highway 99, Investigation Underway Nearby Clinton Avenue
A 25 year old Fresno man was struck and killed while walking in a northbound lane of Highway 99 south of Clinton Avenue on the night of November 19, 2025, local authorities said. The collision highlights ongoing concerns about pedestrian safety and traffic management along this busy corridor, as investigators continue work and toxicology results remain pending.
Fresno County authorities identified the pedestrian killed in a late night collision on November 19, 2025 as 25 year old Manuel Flores of Fresno. The California Highway Patrol said officers were alerted around 10:30 p.m. that evening. Before emergency responders arrived, Flores was struck by a northbound semi truck while walking in a northbound lane of Highway 99 just south of Clinton Avenue. Emergency personnel pronounced Flores dead at the scene.
The semi driver, a 21 year old, remained at the scene and cooperated with investigators, the CHP reported. Toxicology testing for the driver is pending as the investigation continues. CHP officials temporarily closed northbound lanes of Highway 99 while they processed the scene and conducted their inquiry. The Fresno County Sheriff Coroner's Office provided identification and local outlets issued updates as investigators worked through the following days.
The crash occurred on one of the region's major freight and commuter routes, where vehicles travel at highway speeds and pedestrian traffic is rare but vulnerable. For residents, the incident raises immediate questions about safety along Highway 99 near Clinton Avenue and other stretches where sidewalks and safe crossings are limited. The loss of a local resident also reverberates through families and communities who depend on the corridor for daily travel and commerce.
Beyond the immediate investigation, the collision underscores broader public health concerns about pedestrian risk on high speed roadways, the interaction of pedestrians with freight traffic, and the capacity of infrastructure to protect people walking. Transportation planners and public health officials often point to improved lighting, designated crossings, sidewalks, traffic calming and expanded transit options as measures that reduce pedestrian injuries and deaths. Community advocates also note the need for coordinated outreach and services for people at risk on busy roadways.
Authorities continue to investigate the circumstances of the collision. Toxicology results and final findings from the CHP and the coroner will inform whether charges or additional safety recommendations follow. Local residents are urged to use caution when walking near highway corridors and to follow updates from law enforcement as the inquiry proceeds.
